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Combating food poisoning through live animals          

UK scientists have discovered a new way to combat food poisoning, by targeting it in living animals using beneficial bacteria. (14-4-04)

Probiotics provide fresh hope for destroying food poisoning bacteria in poultry before it enters the food chain.Scientists at the Institute of Food Research (IFR) have
discovered that the probiotic Lactobacillus johnsonii clears the pathogenic bacterium Clostridium perfringens from the gut of chicks. This bacterium can cause lesions in
chicks as well as causing food poisoning in humans.

"Some poultry feed already contains probiotic bacteria, but an undefined mixture that gives inconsistent results. This research is exciting because we have used a single
strain and shown that it can be targeted to eliminate a specific pathogen", said Dr Arjan Narbad, Research Scientist at the Institute of Food Research (IFR).

The probiotic also reduced colonisation of the small intestine by E. coli, but did not clear it completely.

The scientists screened thousands of "commensal" bacteria from the adult chicken gut to identify strains that might competitively exclude "bad" bacteria. Lactobacillus
johnsonii showed particular promise, and the IFR teamed up with the Veterinary Laboratories Agency to test its potential.

"For decades we have known that naturally-occurring bacteria in adult chickens can prevent pathogens from colonising in younger birds, whose gut flora is not yet well
developed. But we have not known which bacteria are most effective", said Dr Narbad. "We are particularly pleased to have identified a strain to combat Clostridium
perfringens because it can not only cause food poisoning in humans, but can cause illness in chicks".

Clostridium perfringens is naturally present in the chicken gut, normally without causing disease. Sometimes the bacteria produce toxins, and scientists believe these are
what cause the disease necrotic enteritis. Necrotic enteritis has a number of symptoms in poultry, including poor weight gain and ulcers. In humans it causes intense
abdominal cramps and diarrhoea, sometimes accompanied by vomiting.

British and European farmers are being encouraged to reduce their use of antibiotics in animal feed, and this research provides one viable alternative. Probiotic bacteria could
have additional health benefits for poultry, such as stimulating the immune system and improving the rate of growth.


 
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